NM-Carbomer as Excipinets for Ophthalmic Applications
challenging, endeavors a
formulator can take on. Anhui Newman is well-equipped to meet your needs for
ophthalmic formulation development, in both the anterior and posterior segments
of the eye
.NM-Carbomer products are
versatile and efficient in complex topical mucosal formulations. These
monograph-compliant, mucoadhesive excipients are compatible with most active
pharmaceutical ingredients (APIs) and provide essential properties for
effective ocular formulation development, including:
Bioadhesion / Mucoadhesion – maximize drug absorption by prolonging contact time with the eye, which can increase bioavailability, reduce dosing frequency, and subsequently improve patient compliance
Versatility – compatible with a wide variety of acidic, basic, and neutral APIs across a broad pH range while providing customizable rheology and viscosity for your product
Emulsification – ability to suspend oils in solution and suitable salt tolerance, which are important qualities for many topical products such as eye drops
Non-irritating and non-toxic – enhances patient comfort and safety
All polymers listed in the chart below are
suitable for use in ocular applications and are present in ophthalmic
commercialized products. Ocular applications can include solutions,
suspensions, emulsions, and gels.
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NM-Carbomers asOphthalmic Care Excipients
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Product
Trade Name
|
Polymerization
Solvents1
|
China
(ChP)
|
Europe
(Ph. Eur.)
|
United States
(USP/NF)
|
|
NM-Carbomer
981G
|
Cosolvent
|
Carbomer Homopolymer
Type A
|
Carbomers
|
Carbomer Homopolymer
Type A
|
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NM-Carbomer
980G
|
Cosolvent
|
Carbomer Homopolymer
Type C
|
Carbomers
|
Carbomer Homopolymer
Type C
|
|
NM-Carbomer
971P
|
Ethyl Acetate
|
Carbomer Homopolymer
Type A
|
Carbomers
|
Carbomer Homopolymer
Type A
|
|
NM-Carbomer
974P
|
Ethyl Acetate
|
Carbomer Homopolymer
Type B
|
Carbomers
|
Carbomer Homopolymer
Type B
|
|
NM-Carbomer 934P
|
Cosolvent
|
Carbomer Homopolymer
Type B
|
Carbomers
|
Carbomer Homopolymer
Type B
|
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NM-Carbomer
2020G
|
Cosolvent
|
Carbomer Interpolymer
Type B
|
_
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Carbomer Interpolymer
Type B
|
|
NM-Carbomer
1382G
|
CoSolvent
|
Carbomer Copolymer
Type B
|
_
|
Carbomer Copolymer
Type B
|
|
NM-Carbomer
TR-1 P
|
Cosolvent
|
Carbomer Copolymer
Type B
|
_
|
Carbomer Copolymer
Type B
|
|
NM-Carbomer
TR-2 P
|
Cosolvent
|
Carbomer Copolymer
Type A
|
_
|
Carbomer Copolymer
Type A
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1 Cosolvent = mixture of Ethyl acetate (class III solvent) and Cyclohexane
(class II solvent).
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Carbomer Copolymer Type C
Carbomer Copolymer Type C
Including NM-Carbomer TR-1P, and NM-Carbomer 1382GH
And meeting the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer
Copolymer Type C
China Pharmacopeia (ChP) monograph for Carbomer Copolymer Type C
General Product Characteristics
Appearance: White fluffy powder
Odor: Slightly acetic
Read More
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Carbomer Copolymer Type B
Carbomer Copolymer Type B
Including NM-Carbomer
TR-1P, and NM-Carbomer 1382G
And meeting the current edition of the following monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer
Copolymer Type B
China
Pharmacopeia (ChP) monograph for Carbomer Copolymer Type B
General
Product Characteristics
Appearance: White fluffy
powder
Odor: Slightly acetic
Read More
-
Carbomer Homopolymer Type B
Carbomer Homopolymer Type B
Including
NM-Carbomer 934P, NM-Carbomer974P
And meets the current edition of the following monographs:
United States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer Homopolymer Type B
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type B
Japanese Pharmaceutical Excipients (JPE) Monograph for Carboxyvinyl Polymer
General Product Characteristics
Appearance: White, fluffy powder
Odor: Slightly acetic
Read More
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Carbomer Homopolymer Type A
Carbomer Homopolymer Type A
Including
NM-Carbomer 971P,NM-Carbomer 71G and NM-Carbomer 981G.
And meets the current edition of the following
monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer Homopolymer Type A
European Pharmacopeia (Ph. Eur.) monograph
for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type A
Japanese Pharmaceutical Excipients (JPE) monograph for Carboxyvinyl Polymer
General Product
Characteristics
Appearance: White, fluffy
powder
Odor:
Slightly acetic
Read More
-
Carbomer Homopolymer Type C
Carbomer Homopolymer Type C
NM-Carbomer
980G
Meeting the current edition of the following monographs:
United
States Pharmacopeia/National Formulary (USP/NF) monograph for Carbomer
Homopolymer TypeC (Note: The previous USP/NF compendial name for this product
was Carbomer 940.)
European
Pharmacopeia (Ph. Eur.) monograph for Carbomers
China
Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type C
Japanese Pharmaceutical Excipients (JPE) Monograph for Carboxyvinyl Polymer
General
Product Characteristics
Appearance: White
fluffy powder
Odor: Slightly
acetic
Read More
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Carbomer 934P
NM-Carbomer
934P
NM-Carbomer
934P meets the current
edition of the following monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer Homopolymer Type B
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
Chinese
Pharmacopoeia (ChP.)
monograph for Carbomer Homopolymer Type B
INCI Name:
Carbomer
Appearance: White fluffy
powder
Odor: Slightly acetic
Read More
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Carbomer 971P
NM-Carbomer
971P
NM-Carbomer971P/Carbopol 971P polymers meets the current edition of the following
monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer Homopolymer Type A
European Pharmacopeia (Ph. Eur.) monograph
for Carbomers
China Pharmacopeia (ChP) monograph for Carbomer Homopolymer Type A
General Product
Characteristics
Appearance: White,
fluffy powder
Odor: Slightly acetic
Read More
-
NM-Carbomer 974P
NM-Carbomer
974P
NM-Carbomer
974P meets the current
edition of the following monographs:
United States Pharmacopeia/National
Formulary (USP/NF) monograph for Carbomer Homopolymer Type B(Note: The
previous USP/NF compendial name for this product was Carbomer /carbopol 934P.)
European Pharmacopeia (Ph. Eur.) monograph for Carbomers
Chinese
Pharmacopoeia (ChP.)
monograph for Carbomer Homopolymer Type B
General Product Characteristic
Appearance: White fluffy
powder
Odor: Slightly acetic
Read More
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